The Use of cineMRI to Evaluate Botox in Patients With Medication Refractory Overactive Bladder

Status unconfirmed · Not applicable

Conditions studied: Overactive Bladder

In brief

With the goal of providing improved treatment to patients with overactive bladder symptoms (OAB), the investigators seek to apply the new technology of time-resolved (cine) MRI combined with urodynamics (UDS) to understand the exact effect of intravesical botulinum toxin on bladder physiology. The investigators will specifically aim to assess the physiological mechanism by which intravesical botulinum alleviates urgency and urge incontinence symptoms in women with OAB refractory to medical therapy.

Key facts

Study ID

NCT02315950

Run by

Cedars-Sinai Medical Center

People needed

10

Starts

2014-12-01

Expected to finish

2025-12-01

Last updated by the study team

2018-07-18

Who can join

Age: 21 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Female
• Age 21 years or older
• Overactive bladder symptoms

You may not qualify if…

• Age less than 21 years
• Inability to give informed consent
• Claustrophobic

Where it is running

• Cedars-Sinai Medical Center — Beverly Hills, California, United States (enrolling)

Full record on ClinicalTrials.gov

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