Hearts and Minds in HIV
Completed · Not applicable
Conditions studied: HIV
In brief
The purpose of this study is to see if walking is effective for improving memory, concentration thinking abilities, physical function and quality of life of adults 50 years of age and older living with HIV.
Key facts
- Study ID
- NCT02315742
- Run by
- Emory University
- People needed
- 25
- Starts
- 2016-02-01
- Expected to finish
- 2017-04-01
- Last updated by the study team
- 2017-05-08
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- men and women aged 50 and over with 2 CVD risk factors (i.e., obesity, hypertension, hyperlipidemia) who are diagnosed with HIV/AIDS and willing to participate
- English speaking
- live independently and within a 30 mile radius of Atlanta
- not involved in any structured exercise program or exercising 3 or more times per week for a minimum of 30 minutes
- not involved in any weight loss program
- not hospitalized within the last 60-days
- clinically stable (absence of viral load and no active opportunistic infection), on ART 6 months before enrollment and a screening MOCA score ≤ 24 indicating mild cognitive impairment
You may not qualify if…
- non sedentary (defined as engaging in > 30 minutes of moderately strenuous exercise 3 times or more a week)
- medical or physical condition that would preclude participation in the exercise component of the study (e.g., severe arthritis or mobility problems, uncontrolled hypertension or diabetes, renal failure, or a history of angina with activity
- ischemic changes or inappropriate BP changes on BL exercise (modified Balke) treadmill test
- on corticosteroids, experiencing acute inflammation at time of baseline or follow-up testing (this will result in rescheduling of testing if no other exclusion criteria apply)
- presence of current opportunistic infection
- any terminal illness
- regular use of anti-inflammatory medications such as non-steroidal anti-inflammatory agents
- women who are pregnant
- severe learning disabilities, intellectual disabilities, psychotic disorders to minimize confounding effects on neurocognitive data
- confounding neuro-medical conditions (e.g., active CNS opportunistic infections, seizure disorders, head injury with loss of consciousness greater than 30 minutes, intracranial neoplasms, stroke with neurological or neuropsychiatric sequelae, and non-HIV-associated dementias)
- active substance abuse and major depression
Where it is running
- The Ponce de Leon Center of the Grady Health System — Atlanta, Georgia, United States
- AbsoluteCARE, Inc. — Atlanta, Georgia, United States
- Emory Hospital Infectious Diseases Clinic — Atlanta, Georgia, United States
Full record on ClinicalTrials.gov
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