Point of Care Testing of Inflammatory Markers in Tears
Completed
Conditions studied: Dry Eye Syndrome
In brief
To evaluate the use of a point of care device to measure markers of inflammation in various eye conditions. In particular, matrix metalloproteinase-9 (MMP-9) will be measured. MMP-9 is an enzyme that plays a role in inflammation. The value obtained with the point of care device will be correlated with values obtained using gel electrophoresis to measure MMP-9 from the same sample. These data will be compared to clinical exam findings and questionnaires to help the investigators better understand the role of this marker of inflammation in eye diseases and possibly improve diagnostic abilities.
Key facts
- Study ID
- NCT02315079
- Run by
- University of Florida
- People needed
- 63
- Starts
- 2015-01-01
- Expected to finish
- 2017-01-01
- Last updated by the study team
- 2019-07-24
Who can join
Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Patients that present to clinic for evaluation. Patients with and without evidence of eye inflammation will be eligible for this study.
You may not qualify if…
- Patients outside the age limits will not be eligible for the study
Where it is running
- University of Florida, Department of Ophthalmology — Gainesville, Florida, United States
Full record on ClinicalTrials.gov
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