Esophageal Absorption in EoE

Stopped early · Not applicable

Conditions studied: Eosinophilic Esophagitis

In brief

To determine how the esophagus in active and inactive stages of eosinophilic esophagitis tranmit fluids.

Key facts

Study ID

NCT02314455

Run by

Mayo Clinic

People needed

14

Starts

2014-09-01

Expected to finish

2016-07-01

Last updated by the study team

2016-07-21

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients between the ages of 18 and 80 with eosinophilic esophagitis diagnosed by a combination of compatible symptoms, endoscopic findings, histology, and lack of response to proton pump inhibitors or negative pH study
• endoscopy with esophageal and duodenal biopsies within two weeks of performance of this study
• Patients between the ages of 18 and 80 with eosinophilic esophagitis diagnosed by a combination of compatible symptoms, endoscopic findings, histology, and lack of response to proton pump inhibitors or negative pH study, and are now in histologic remission( <15phf) by the use of steroids or the six food elimination diet.
• Volunteers will be selected for not having any history of esophageal symptoms

You may not qualify if…

• Vulnerable populations, such as those with diminished mental acuity, will be excluded.
• Patients taking Nsaids within 48 hours of the d-xylose testing
• artificial sweeteners within 48 hours of the d-xylose testing
• History of IBD
• Currently smoking or history of smoking
• History of Celiac disease
• Bacterial overgrowth,
• motility disorders
• other diffuse small bowel diseases.

Where it is running

• Mayo Clinic in Rochester — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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