The Leaky Lung Test

Completed · Early Phase 1

Conditions studied: Asthma, Allergy, Reactive Airway Disease, Lung Diseases, Obstructive

In brief

This is a clinical trial designed to test the hypothesis that measuring the absorption and excretion of inhaled mannitol will provide a clinically useful marker of airway epithelial permeability in asthma.

Key facts

Study ID

NCT02306473

Run by

University of Rochester

People needed

100

Starts

2015-10-01

Expected to finish

2017-12-01

Last updated by the study team

2018-01-04

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• >5 pack year history of tobacco use or active smoking.
• Other chronic or active lung diseases (e.g. COPD, pulmonary fibrosis, lung cancer)
• History of significant renal insufficiency of liver disease
• Asthma subjects with severe disease according to NAEPP guidelines (e.g. severe ongoing symptoms despite high-dose inhaled or oral glucocorticoids)
• Asthma subjects with a baseline FEV1<65% predicted
• Asthma subjects unwilling or unable to withhold medications prior to testing
• Pregnant women.

Where it is running

• University of Rochester Medical Center — Rochester, New York, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.