Roux-en-Y Gastric Bypass and Weight Regain

Completed

Conditions studied: Obesity

In brief

This study compares eating behaviors, meal size, and the size of the gastric pouch and connection between the gastric pouch and small intestine in patients who had gastric bypass surgery two or more years ago and regained weight compared with patients who had gastric bypass surgery two or more years ago and maintained their weight loss.

Key facts

Study ID

NCT02302898

Run by

Washington University School of Medicine

People needed

2

Starts

2015-10-01

Expected to finish

2016-06-01

Last updated by the study team

2018-04-09

Who can join

Age: 21 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages of 21 and 60
• Laparoscopic RYGB surgery >2 years before screening
• Regained >20% weight from their maximum weight lost after surgery or maintained at least 90% weight loss from the maximum weight loss after surgery

You may not qualify if…

• Allergy to lidocaine, nut allergies, milk intolerance or any other food allergies/restrictions that are included in our test meals
• A history of alcohol abuse
• Currently consuming >20 gm of alcohol per day
• Greater than 2 points on the MAST
• Severe organ dysfunction
• Anemia (hemoglobin <10mg/dl)
• PT, PTT and INR > 1.5x UNL
• Triglycerides > 400
• LFT > 2x UNL
• Women who are pregnant or lactating
• Participants that smoke greater than 20 pack years
• Actively using illegal drugs
• Depression or other psychological disorders that are untreated
• Diabetics receiving Insulin
• Patients that have been hospitalized and/or had surgery in the last three months that may be unstable (PI will determine this at Physical Exam)

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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