Treating New Learning and Memory Deficits in Progressive Multiple Sclerosis (MS)

Completed · Not applicable · Has a placebo group

Conditions studied: Multiple Sclerosis, Progressive, Cognition - Other, Memory Impairment

In brief

This study is a double-blind placebo-controlled randomized clinical trial (RCT) to provide Class I evidence in support of or in refute of the efficacy of the modified Story Memory Technique (mSMT) in persons with progressive MS, with outcome measured through three mechanisms: (1) a traditional neuropsychological evaluation (NPE) (2) an assessment of global functioning (AGF) examining the impact of the treatment on daily activities, and (3) an optional functional magnetic resonance imaging (fMRI) scan.

Key facts

Study ID

NCT02301247

Run by

Kessler Foundation

People needed

32

Starts

2014-11-01

Expected to finish

2017-04-02

Last updated by the study team

2017-07-02

Who can join

Age: 30 and older, up to 59. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• between the ages of 30 and 59
• diagnosed with Progressive Multiple Sclerosis
• have visual acuity of better then 20/60 in worse eye

You may not qualify if…

• has a prior stroke or neurological injury/disease (brain tumor, epilepsy, traumatic brain injury).
• has a history of psychiatric illness (for example, bipolar disorder, schizophrenia, or psychosis).
• currently taking medications such as: steroids, benzodiazepines, and neuroleptics. .
• difficulty with vision, eyesight worse then 20/60, or has diminished sight in visual field, double vision, or nystagmus.

Where it is running

• Kessler Foundation — West Orange, New Jersey, United States

Full record on ClinicalTrials.gov

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