Pharmacokinetics of Intranasal Ketorolac in Children

Stopped early · Phase 1

Conditions studied: Evaluating Pharmacokinetics of Intranasal Ketorolac, Pain

In brief

Ketorolac is a non-steroidal anti-inflammatory drug (NSAID) that is typically given to both adults and children by the intravenous (IV) or intramuscular (IM) route for analgesic purposes. Ketorolac can also be given by the intranasal (IN) route using a mucosal atomization device (MAD). We aim to study the pharmacokinetics of ketorolac when administered by the IN route using the MAD.

Key facts

Study ID

NCT02297906

Run by

Columbia University

People needed

18

Starts

2015-02-01

Expected to finish

2017-11-29

Last updated by the study team

2019-01-17

Who can join

Age: 8 and older, up to 17. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Present to the emergency department with a painful condition for which the treating physician decides to administer ketorolac as part of their usual care.

You may not qualify if…

• Known allergy to ketorolac
• Contraindication to receiving ketorolac
• Receiving any NSAID within the past 6 hours
• Presence of an intranasal obstruction that cannot be readily cleared using suction or nose-blowing
• Inability to speak English or Spanish
• Critical illness

Where it is running

• New York Presbyterian Morgan Stanley Children's Hospital — New York, New York, United States

Full record on ClinicalTrials.gov

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