Effect of Eleclazine (GS-6615) on Exercise Capacity in Subjects With Symptomatic Hypertrophic Cardiomyopathy
Stopped early · Phase 2/Phase 3 · Has a placebo group
Conditions studied: Hypertrophic Cardiomyopathy
In brief
The primary objective of this study was to evaluate the effect of eleclazine (GS-6615) on exercise capacity as measured by Peak oxygen uptake (VO2) achieved during cardiopulmonary exercise testing (CPET), in participants with symptomatic hypertrophic cardiomyopathy (HCM).
Key facts
- Study ID
- NCT02291237
- Run by
- Gilead Sciences
- People needed
- 172
- Starts
- 2015-02-05
- Expected to finish
- 2017-02-17
- Last updated by the study team
- 2018-09-24
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
Where it is running
- Cedars-Sinai Heart Institute — Los Angeles, California, United States
- University of California Los Angeles — Los Angeles, California, United States
- Stanford University — Stanford, California, United States
- Yale New Haven Hospital — New Haven, Connecticut, United States
- Athens Regional Medical Center — Athens, Georgia, United States
- Northwestern Memorial Hospital — Chicago, Illinois, United States
- University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
- Brigham & Women's Hospital and Harvard Medical School — Boston, Massachusetts, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
- Tufts Medical Center — Boston, Massachusetts, United States
- Washington University School of Medicine — St Louis, Missouri, United States
- Morristown Medical Center — Morristown, New Jersey, United States
- Columbia University Medical Center/ New York Presbyterian — New York, New York, United States
- NYU School of Medicine Pediatrics — New York, New York, United States
- Duke Health Center at Southpoint — Durham, North Carolina, United States
- Oregon Health and Science University — Portland, Oregon, United States
- St. Luke's University Health Network — Bethlehem, Pennsylvania, United States
- University of Pittsburgh Medical Center — Pittsburgh, Pennsylvania, United States
- St. Thomas Research Institute — Nashville, Tennessee, United States
- Vanderbilt University Medical Center — Nashville, Tennessee, United States
- Houston Methodist Hospital — Houston, Texas, United States
- Texas Heart Institute — Houston, Texas, United States
- UT Southwestern Medical Center — Houston, Texas, United States
- University of Washington — Seattle, Washington, United States
- Marshfield Clinic Research Institute — Marshfield, Wisconsin, United States
Full record on ClinicalTrials.gov
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