Minority Health Genomics and Translational Research Bio-Repository Database (MH-GRID)-2.0

Completed

Conditions studied: Hypertension

In brief

Background: \- High blood pressure is a common problem. It can cause heart attacks, strokes, and kidney failure. It affects African Americans more than other racial groups. Data were collected from over a thousand African Americans across the country. The data were put into a database (MH-GRID). The data were about genes, diet, sleep, body mass index. They also cover stress and access to healthy foods and parks. Researchers at NIH will study these data in new ways. They want to learn more about the connection between African Americans and high blood pressure. Objective: \- To study MH-GRID data to find the causes of severe high blood pressure and other cardio-metabolic problems in people of African ancestry. Eligibility: \- African Americans age 30 55 with severe high blood pressure were used in the MH-GRID study. No new participants will be enrolled in this study. Design: \- Researchers will examine data from the MH-GRID study.

Key facts

Study ID

NCT02290392

Run by

National Heart, Lung, and Blood Institute (NHLBI)

People needed

1692

Starts

2014-11-11

Expected to finish

2019-07-16

Last updated by the study team

2026-08-03

Who can join

Age: 30 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Exclusion criteria involved patients with secondary forms of HTN, primary forms of kidney disease or major co-morbidities (e.g. diabetes, heart failure, end-stage renal failure, HIV, and liver disease)
• Children <18 were not enrolled in the protocol

Where it is running

• National Heart, Lung and Blood Institute (NHLBI) — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

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