PET/MRI and PET/CT in Diagnosing Younger Patients With Cancer

Completed · Not applicable

Conditions studied: Childhood Cancer

In brief

This pilot clinical trial studies how well positron emission tomography (PET)/magnetic resonance imaging (MRI) works compared to PET/computed tomography (CT) in diagnosing younger patients with cancer. PET/MRI and PET/CT are procedures that combine the pictures from a PET scan and an MRI scan or a CT scan. The PET and MRI scans or PET and CT scans are done at the same time with the same machine. The combined scans give more detailed pictures of areas inside the body than either scan gives by itself. It is not yet known whether PET/MRI works better than PET/CT in diagnosing younger patients with cancer.

Key facts

Study ID

NCT02287636

Run by

Case Comprehensive Cancer Center

People needed

13

Starts

2013-04-01

Expected to finish

2016-04-01

Last updated by the study team

2020-02-24

Who can join

Age: any, up to 17. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who are referred by their physician for clinically indicated diagnostic fludeoxyglucose F 18 (18F-FDG) PET/CT (with or without clinically indicated diagnostic MRI)
• Subjects with malignancies including hematologic disorders
• Subjects NOT requiring sedation or anesthesia
• Stable physical medical conditions (patients conscious and comfortable, scheduled for an elective diagnostic imaging)

You may not qualify if…

• Subjects who are unable or unwilling to give their assent to both examinations if > 7 years old
• Subjects requiring general anesthesia or sedation in order to undergo PET/CT or MRI
• Subjects unable to undergo magnetic resonance (MR) scanning due to exclusion by University Hospitals-Case Medical Center restriction policies for Magnetic Resonance Imaging (UHCMC MRI restriction policies) as mentioned in the standard UHCMC MRI informed consent form
• Previously known allergies against MRI contrast agents (exclusion criterion only for contrast enhanced MRI)
• Pregnant or breast feeding subjects, as determined by standard questionnaire administered prior to scanning

Where it is running

• Case Medical Center, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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