The Regulation of Pulmonary Vascular Resistance in Patients With Heart Failure

Completed

Conditions studied: Diastolic Heart Failure, Pulmonary Hypertension

In brief

Peripheral blood and blood following a pulmonary wedge pressure will be obtained from patients undergoing right heart catheterizations.

Key facts

Study ID

NCT02275793

Run by

University of Toledo Health Science Campus

People needed

90

Starts

2011-09-01

Expected to finish

2015-09-01

Last updated by the study team

2019-09-18

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age >18 years
• Ability to provide informed consent.
• Presenting for cardiac catheterization for evaluation of heart disease
• Ejection Fraction > 50%

You may not qualify if…

• Unable to provide informed consent.
• Unable or unwilling to comply with the protocol and follow up.
• Infiltrative cardiomyopathy
• Constrictive pericarditis
• Severe valvular disease
• Comorbid status with life expectancy <3 years
• Right ventricular dysplasia
• Congenital heart disease
• On immunosuppressive drugs.
• Patients who has heart transplant.
• Ejection Fraction < 50%
• Mean Pulmonary Artery Pressure <25
• Wedge pressure <15

Where it is running

• University of Toledo, Health Science Campus — Toledo, Ohio, United States

Full record on ClinicalTrials.gov

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