Persistent Post-Surgical Pain in Women With BrCA
Completed
Conditions studied: Breast Cancer, Chronic Pain
In brief
Women with early-stage breast cancer (BrCA) are surviving longer, but many experience symptoms after curative treatments. Approximately 50% of BrCA survivors experience persistent pain post-surgery. Identifying individuals at high risk for long-term symptoms is important for restoring function and enhancing quality of life. This pilot study will investigate psychological (depression, anxiety, catastrophizing) and biological (inflammatory markers, gut microbiome, pain sensitivity) correlates of persistent post-surgical pain in women participants with early-stage BrCA. The investigators will also investigate the type of surgery that participants had and whether it is related to persistent pain. The investigators plan explore these factors over time.
Key facts
- Study ID
- NCT02266082
- Run by
- University of Florida
- People needed
- 5
- Starts
- 2015-05-01
- Expected to finish
- 2016-12-01
- Last updated by the study team
- 2018-12-28
Who can join
Age: 40 and older, up to 75. Sex: female. Healthy volunteers: not accepted.
You may qualify if…
- diagnosed with breast cancer (based on biopsy)
- scheduled for surgery (either lumpectomy or mastectomy, with anticipated sentinel node dissection and possible axillary lymph node dissection)
- between 40 - 75 years of age.
You may not qualify if…
- history of previous cancer, chemotherapy or radiation, cardiovascular or neurological conditions, bowel surgery, or hospitalization for mental illness in past year
- chronic pain conditions or daily use of opioids
- pregnant or nursing
- diagnosed with metastatic breast cancer after surgery and cancer staging is completed (post-lymph node dissection)
- any other condition that in the opinion of the principal investigator may compromise participation in this study
Where it is running
- University of Florida — Gainesville, Florida, United States
Full record on ClinicalTrials.gov
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