Augmenting Treatment Effects of Voice Therapy in Parkinson Disease
Status unconfirmed · Not applicable · Has a placebo group
Conditions studied: Parkinson Disease
In brief
The purpose of this study is to evaluate the impact of a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) on voice/speech treatment in people with Parkinson's Disease (PD), through the use of speech and voice analysis, examination of voice box, and brain imaging methods.
Key facts
- Study ID
- NCT02265315
- Run by
- Le Bonheur Children's Hospital
- People needed
- 70
- Starts
- 2014-10-01
- Expected to finish
- 2021-06-30
- Last updated by the study team
- 2020-09-22
Who can join
Age: 45 and older, up to 80. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Individuals with Idiopathic Parkinson's disease (IPD) between the ages of 45 and 80 years with moderate to severe hypophonia
- None or mild cognitive impairment or depression
- Stable medication therapy for at least 3 months. Must be "optimally medicated" at the start of the study. This means that there should be no change in mediction type or dosage in 3 months prior to enrolling in the study. The medications should not be causing significant or serious advese effects
You may not qualify if…
- History of drug abuse or neurological condition other than or in addition to IPD (for example stroke)
- Individuals with advanced IPD (stage V) or who had LSVT within 3 years
- Pregnant females
- History of seizures, history of major head trauma, metal objects implanted in the head, ferrous metal filings in the eye, brain damage, inflammation of the brain, cardiac pacemaker, implanted medication pump, cardiac lines, heart disease, currently taking certain types of medication for depression or seizures (tricyclic antidepressants or neuroleptics which lower seizure threshold
Where it is running
- LeBonheur Children Hospital — Memphis, Tennessee, United States
Full record on ClinicalTrials.gov
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