Resveratrol and Human Hepatocyte Function in Cancer

Withdrawn before enrolling · Phase 1/Phase 2 · Has a placebo group

Conditions studied: Liver Cancer

In brief

The purpose of this study is to determine if Resveratrol, a nutritional supplement, shows a beneficial effect in the cellular function of normal liver cells and diseased liver cells (cancer cells) in samples of liver tissue taken during elective liver surgery. Outcomes based on 3 measures will test the hypothesis that Resveratrol when used as a nutritional supplement will 1)improve metabolic function in liver cells, 2)reduce cellular growth and proliferation of cancer cells, 3)decrease inflammation in the liver.

Key facts

Study ID

NCT02261844

Run by

University of Louisville

People needed

0

Starts

2015-12-01

Expected to finish

2016-06-01

Last updated by the study team

2017-03-30

Who can join

Age: 21 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Undergoing elective liver resection for liver cancer

You may not qualify if…

• Inability to speak or read English
• Sclerosing cholangitis, hemochromatosis, hepatic encephalopathy, acute hepatic failure
• History of daily alcohol intake
• Presence of human immunodeficiency virus
• Presence of significant renal dysfunction as defined by baseline serum creatinine > 2.0 mg/dl or need/impending need for chronic dialysis therapy
• Known allergy to the study medication
• Pregnancy, lactating women, women contemplating pregnancy during the study period

Where it is running

• University of Louisville — Louisville, Kentucky, United States

Full record on ClinicalTrials.gov

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