A Safety and Efficacy Study of OnabotulinumtoxinA in Forehead and Glabellar Facial Rhytides

Completed · Phase 3 · Has a placebo group

Conditions studied: Forehead Rhytides, Glabellar Rhytides

In brief

This is a safety and efficacy study of onabotulinumtoxinA in subjects with forehead and glabellar facial rhytides (frown lines).

Key facts

Study ID

NCT02261467

Run by

Allergan

People needed

421

Starts

2014-10-21

Expected to finish

2016-04-26

Last updated by the study team

2019-01-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Moderate to severe forehead and glabellar lines
• Willing to have facial photos taken

You may not qualify if…

• Prior exposure to botulinum toxin of any serotype for any indication
• Anticipated need for treatment with botulinum toxin of any serotype for any indication during the study, other than study treatment
• Diagnosis of myasthenia gravis, Eaton-Lambert syndrome, or amyotrophic lateral sclerosis
• Any facial resurfacing laser or light treatment, microdermabrasion, or superficial peels in the past 3 months
• Any medium depth or deep depth facial chemical peels; facial skin resurfacing; or permanent facial make-up in the past 6 months
• Any nonpermanent soft tissue fillers, or treatment with oral retinoids in the past year
• Prior face lift, thread lift, eyebrow lift, or related procedures (eg, eyelid and/or eyebrow surgery)
• Prior facial treatment with permanent soft tissue fillers, synthetic implants (eg, Gore-Tex®), and/or fat transplantation

Where it is running

• Total Skin and Beauty Dermatology Center, PC — Birmingham, Alabama, United States
• Advanced Research Associates — Glendale, Arizona, United States
• Clinical Science Institute — Santa Monica, California, United States
• About Skin Dermatology and DermSurgery, PC — Greenwood Village, Colorado, United States
• Steven Fagien, MD, PA — Boca Raton, Florida, United States
• Laser & Skin Surgery Center of Indiana — Carmel, Indiana, United States
• Coleman Center For Cosmetic Dermatologic Surgery — Metairie, Louisiana, United States
• Henry Ford Medical Center — West Bloomfield, Michigan, United States
• NW Dermatology and Research Center — Portland, Oregon, United States
• Carruthers Dermatology Centre — Vancouver, British Columbia, Canada
• Dr. Shannon Humphrey, Inc. — Vancouver, British Columbia, Canada
• Jean Carruthers Cosmetic Dermatology — Vancouver, British Columbia, Canada
• Sweat Clinics of Canada — Toronto, Ontario, Canada
• Arthur Swift Research, Inc. — Westmount, Quebec, Canada
• Aesthetic Surgery Ireland — Dublin, Ireland
• Beacon Face and Dermatology Clinic — Dublin, Ireland

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.