Effect of Breaking up Prolonged Sitting on Metabolic Flexibility
Completed · Not applicable
Conditions studied: Health Behavior
In brief
The investigators propose in this project to determine the effect of 3 days of frequent interruption of prolonged sitting on metabolic health in healthy overweight sedentary adults (n=24), as compared to 3 days including a single long bout of isocaloric exercise or a control condition where subjects do not exercise but are subjected to prolonged sitting. The investigators believe that this proposed project will provide an initial evidence base for the health benefits of breaking up prolonged sitting with short bursts of moderate-intensity activity, like walking.
Key facts
- Study ID
- NCT02258438
- Run by
- University of Colorado, Denver
- People needed
- 28
- Starts
- 2014-10-08
- Expected to finish
- 2017-09-01
- Last updated by the study team
- 2021-04-30
Who can join
Age: 19 and older, up to 45. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- overweight but weight stable (less than +/- 3kg over previous 6 months) male and female adults (n=24) will be recruited.
- age between 19-45 years old,
- a BMI of 27-33 kg/m2,
- inactive (≤ 1.5hr/wk of moderate-to-vigorous activity),
- sedentary (office employees who are spending more than 6hrs/day in sitting position) and
- English-speaking.
You may not qualify if…
- any history of renal, cardiovascular or hepatic diseases,
- type 1 or 2 diabetes,
- cancer,
- pregnancy,
- smoking,
- consumption of drugs or alcohol (>40g/d),
- any medications known to interfere with lipid or energy metabolism,
- known physical activity contraindications, or major illness/physical problems (acute or chronic) that may limit their ability to perform the walking activities and
- menopause (defined as no menses in the prior 6 months). The use of birth pill control will be accepted. Women are asked to avoid pregnancy until completion of Condition C.
Where it is running
- University of Colorado Hospital — Aurora, Colorado, United States
Full record on ClinicalTrials.gov
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