Tolerability of Acthar for the Treatment of Multiple Sclerosis in Relapses (TAMS)

Completed · Not applicable

Conditions studied: Relapsing Remitting Multiple Sclerosis

In brief

Tolerability of Acthar for the Treatment of Multiple Sclerosis Relapses (TAMS)

Key facts

Study ID

NCT02258217

Run by

OhioHealth

People needed

30

Starts

2014-06-01

Expected to finish

2016-12-01

Last updated by the study team

2020-09-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects who have volunteered and consented to participate in the study.
• Subjects who have no contraindication to taking high dose, oral prednisone or Acthar.
• Male or Female subjects age 18 or greater years of age.
• Subjects with Relapsing Remitting Multiple Sclerosis (RRMS) based on 2010 McDonald Criteria.
• Subjects without an active infection (Note: If a patient is found to have an uncomplicated UTI and agrees to start on appropriate antibiotic treatment, they can continue in the study).
• Subjects who are experiencing a protocol defined MS relapse within two weeks of relapse onset.
• Subjects who are able and willing to sign a consent form.

You may not qualify if…

• Subjects who are less than 18 years of age.
• Subjects with any contraindication to taking Acthar.
• Subjects with an active infection other than an uncomplicated urinary tract infection (UTI) (subjects determined to have a UTI who agree to be treated with appropriate antibiotics will not be excluded).
• Subjects with an immune deficiency.
• Subjects with a history of any of the following conditions: gastrointestinal ulcers, diabetes mellitus, gestational diabetes, malignant hypertension or steroid induced psychosis.
• Subjects who are pregnant or breastfeeding.
• Subjects who are unable or unwilling to sign consent form.
• Patient is unable or unwilling to participate in phone and clinic follow up.
• Other factors that in the opinion of the Principal Investigator would exclude the subject from participation in the study.

Where it is running

• OhioHealth — Columbus, Ohio, United States

Full record on ClinicalTrials.gov

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