SYN120 Study to Evaluate Its Safety, Tolerability and Efficacy in Parkinson's Disease Dementia (SYNAPSE)
Completed · Phase 2 · Has a placebo group
Conditions studied: Parkinson's Disease Dementia (PDD)
In brief
The purpose of this study placebo-controlled, randomized, double-blind study is to assess the safety and efficacy of SYN120 in patients with Parkinson's disease dementia (PDD) already treated with a stable dose of a cholinesterase inhibitor.
Key facts
- Study ID
- NCT02258152
- Run by
- Biotie Therapies Inc.
- People needed
- 82
- Starts
- 2014-12-22
- Expected to finish
- 2017-10-03
- Last updated by the study team
- 2019-04-19
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Parkinson's Disease Dementia
- Patient has a routine caregiver
- Taking a stable cholinesterase inhibitor.
- Patient has a Montreal Cognitive Assessment (MoCA) 10-23 inclusive
You may not qualify if…
- History of any significant neurologic or psychiatric disease other than PD
- Any other condition or clinically significant abnormal findings that would make the patient unsuitable for the study
- Unpredictable motor fluctuations that would interfere with administering assessments
Where it is running
- The University of Alabama at Birmingham — Birmingham, Alabama, United States
- Banner Sun Health Research Institute — Sun City, Arizona, United States
- UC San Diego — La Jolla, California, United States
- Parkinson's Disease & Movement Disorder Center of Boca Raton — Boca Raton, Florida, United States
- Augusta University — Augusta, Georgia, United States
- Northwestern University, Feinberg School of Medicine — Chicago, Illinois, United States
- Rush University Medical Center — Chicago, Illinois, United States
- University of Iowa, Carver College of Medicine — Iowa City, Iowa, United States
- Parkinson's Disease & Movement Disorder Center, University of Kansas Medical Center — Kansas City, Kansas, United States
- Department of Neurology, University of Maryland Parkinson's Disease & Movement Disorder Center — Baltimore, Maryland, United States
- Massachusetts General Hospital — Boston, Massachusetts, United States
- Struthers Parkinson's Center — Golden Valley, Minnesota, United States
- Atlantic Neuroscience Institute — Summit, New Jersey, United States
- Duke University — Durham, North Carolina, United States
- Wake Forest Baptist Health Sciences — Winston-Salem, North Carolina, United States
- Parkinson's Disease Movement Disorder Center — Philadelphia, Pennsylvania, United States
- Thomas Jefferson University — Philadelphia, Pennsylvania, United States
- Medical University of South Carolina — Charleston, South Carolina, United States
- Baylor Univeristy — Houston, Texas, United States
- Houston Methodist Neurological Institute/Movement Disorders Clinic — Houston, Texas, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.