Protective Effects of EPI-743 on Noise-Induced Hearing Loss

Completed · Phase 2 · Has a placebo group

Conditions studied: Noise-induced Hearing Loss

In brief

If effective, administration of EPI-743 should have protective effects against temporary noise-induced hearing loss.

Key facts

Study ID

NCT02257983

Run by

Edison Pharmaceuticals Inc

People needed

77

Starts

2014-10-31

Expected to finish

2016-02-29

Last updated by the study team

2020-11-18

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Healthy adults ages 18-30
• Abstention from use of Idebenone, CoQ10, Vitamin E and foods or beverages at least 30 days prior to treatment initiation
• Non-smokers
• Abstention from alcohol from day 0 and throughout the duration of study
• Normal audiology exam
• Subject must be able to swallow size 0 capsules

You may not qualify if…

• Allergy to EPI-743 or sesame oil or nuts
• Any medical disordere that would prevent subject participation
• Any prescription meds other than for contraception or seasonal allergies
• Any significant patient medical history (cancer, cardiovascular, pulmonary, cognitive, ADHD, hx. of migraines, neurological, kidney)
• Fat malabsorption syndromes
• Anticoagulation thereapy within 30 days of enrollment

Where it is running

• University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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