Treatment of Depersonalization Disorder With Repetitive Transcranial Magnetic Stimulation (rTMS)

Withdrawn before enrolling · Phase 2 · Has a placebo group

Conditions studied: Depersonalization Disorder

In brief

This is a randomized controlled trial (RCT) on the efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) in the treatment of Depersonalization Disorder (DPD). TMS applies a magnetic field to the brain for a brief period of time. TMS is a procedure that involves 30 minute-long daily sessions every weekday for a series of weeks. The investigators are testing whether TMS can treat Depersonalization Disorder (DPD).

Key facts

Study ID

NCT02256085

Run by

New York State Psychiatric Institute

People needed

0

Starts

2013-10-01

Expected to finish

2016-12-01

Last updated by the study team

2017-03-24

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female outpatients, 18 to 70 years of age.
• Primary diagnosis of Depersonalization Disorder.
• Duration of the index episode of at least a year.
• Patients currently on DPD medication must be at the same stable dose(s) at least 2 months and be to continue at the same dose(s) through the duration of the study.
• Patients must continue to be under the care of their treating psychiatrist who will be writing prescriptions for concomitant medications through the duration of the study.
• Capable and willing to provide informed consent

You may not qualify if…

• Individuals diagnosed with current Major Depressive Disorder or Panic Disorder.
• Individuals diagnosed with the following conditions: Bipolar Disorder (lifetime), any Psychotic Disorder (lifetime), History of substance abuse or dependence within the past yea (except nicotine and caffeine).
• Individuals with a neurological disorder including, but not limited to: brain lesion; history of seizures; history of cerebrovascular accident; history of stroke; TIA, cerebral aneurysm, Dementia; Parkinson's Disease; Huntington's chorea; Multiple Sclerosis.
• Increased risk of seizure for any reason, including prior head trauma with loss of consciousness for 5 minutes or more
• Cardiac pacemakers, implanted medication pumps, intracardiac lines, or acute, unstable cardiac disease.
• Intracranial implants (e.g. aneurysms clips, shunts, stimulators, cochlear implants, or electrodes) or any other metal object within or near the head, excluding the mouth, that cannot be safely removed.
• History of treatment with rTMS therapy for any disorder.
• If participating in psychotherapy, must have been in stable treatment for at least three months prior to entry into the study, with no anticipation of change in frequency of therapeutic sessions, or the therapeutic focus over the duration of the rTMS trial.
• Known or suspected pregnancy.
• Women who are breast-feeding

Where it is running

• Sophie Davis School of Biomedical Education, City University of New York (CUNY) — New York, New York, United States
• New York State Psychiatric Institute, Experimental Therapeutics — New York, New York, United States

Full record on ClinicalTrials.gov

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