Assessing Insulin Sensitivity and Diabetes Risk in Childhood Cancer Survivors Treated With Abdominal Irradiation

Completed

Conditions studied: Childhood Cancer Survivors Treated With Abdominal Radiation

In brief

The purpose of this study is to better understand the risk factors and causes of diabetes in people who received radiation to the abdomen as children. The investigators hope this information will allow them to improve how they screen people at risk for diabetes and how they treat patients in the future.

Key facts

Study ID

NCT02248779

Run by

Memorial Sloan Kettering Cancer Center

People needed

42

Starts

2014-09-22

Expected to finish

2019-10-09

Last updated by the study team

2019-10-15

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Diagnosis of childhood cancer between 0-21 years of age
• Prior treatment with abdominal radiation at MSKCC
• Two or more years from completion of therapy
• Records of cancer diagnosis and treatment (including radiation records) available

You may not qualify if…

• Known diagnosis of diabetes
• Previous treatment with any radiation impacting the brain (cranial radiation, craniospinal radiation, total body irradiation)
• Neurocognitive deficits that impair ability to give informed consent or assent
• Patients predicted to have difficult intravenous access, who will likely require multiple venipuncture attempts

Where it is running

• Memorial Sloan Kettering Cancer Center — New York, New York, United States

Full record on ClinicalTrials.gov

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