Establishing a Non-invasive Method to Measure Your Heart's Performance

Completed

Conditions studied: Heart Failure

In brief

The purpose of the study is to evaluate a new way to examine cardiac function, using software developed at Caltech. The experimental device is software loaded on an iPhone. The iPhone is used to capture a pulse (waveform) by simply placing the iPhone lightly over the neck where the carotid pulse can be felt. In this study the information collected from the iPhone app is compared to cardiac function data obtained from the current gold standard for measuring cardiac function, cardiac magnetic resonance imaging (MRI). Subjects referred from cardiologists will also generally have echocardiography information available for comparison with the iPhone app. For the study, subjects will have completely non-invasive studies done in one setting: The iPhone app to capture the waveforms (over carotid and radial (wrist) arteries), tonometry (another non-invasive method using a modified stethoscope), standard pulse oximetry, followed by a 30 minute MRI examination of the heart. A second complete study will be done about 6 months after the first. The complete study session takes about 1.5 hours.

Key facts

Study ID

NCT02240979

Run by

Marie Csete MD, PhD

People needed

72

Starts

2014-08-01

Expected to finish

2019-05-01

Last updated by the study team

2019-05-14

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Adult age 18-90, outpatients

You may not qualify if…

• Inability to lie flat for 30 minutes with periodic breath holding
• Metal implants or other standard contraindications to MRI
• Acute cardiac decompensation (active chest pain, shortness of breath)
• Hypotension (SBP<90 mm Hg)
• Claustrophobia
• Patient too large to fit in closed MRI

Where it is running

• Avicena LLC — Pasadena, California, United States
• Huntington Medical Research Institutes MR Imaging Center — Pasadena, California, United States

Full record on ClinicalTrials.gov

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