Detection of Brown Adipose Tissue by Magnetic Resonance Imaging

Completed

Conditions studied: Obesity, Brown Adipose Tissue

In brief

The primary goal of this study is to assess the accuracy of conventional fat fraction proton MRI for the detection of Brown Adipose Tissue (BAT) in healthy subjects using \[18F\]-2-fluoro-2-deoxy-D-glucose (fluorodeoxyglucose) -PET as gold standard. In this pilot study, MRI and PET imaging of BAT of healthy adult volunteers will be performed on a combined PET/MRI scanner under mild cold condition.

Key facts

Study ID

NCT02237872

Run by

University of North Carolina, Chapel Hill

People needed

8

Starts

2015-01-20

Expected to finish

2015-08-27

Last updated by the study team

2025-10-01

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Each subject must be fully informed and have signed consent.
• BMI < 34
• Normal neurological and psychological development / able to give consent
• Willingness to participate in this study

You may not qualify if…

• Subjects less than 18 years of age
• Severe claustrophobia
• Women who are pregnant, nursing an infant or planning to become pregnant in the next 30 days
• People who have a condition that makes MRI unsafe for them (for example, cardiac pacemaker, epicardial pacemaker leads, cochlear implants, metal aneurysm clip, iron filings in your eyes or metal halo devices)
• Have had radiation therapy or chemotherapy in the 2 months prior to PET scan
• Subjects are taking medications that may interfere with BAT detection

Where it is running

• Biomedical Research Imaging Center — Chapel Hill, North Carolina, United States
• Biomedical Research Imaging Center — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

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