Diffusion-Weighted MRI in Staging Patients With Localized Prostate Cancer

Completed · Not applicable

Conditions studied: Adenocarcinoma of the Prostate, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer

In brief

This pilot clinical trial studies how well diffusion-weighted magnetic resonance imaging (MRI) works in staging patients with prostate cancer that has not spread to nearby lymph nodes or other parts of the body. New imaging techniques, such as diffusion-weighted MRI, may be a less invasive way of predicting the stage and grade of prostate cancer.

Key facts

Study ID: NCT02237612
Run by: University of Southern California
People needed: 9
Starts: 2009-01-01
Expected to finish: 2013-03-01
Last updated by the study team: 2014-09-11

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

Biopsy-documented adenocarcinoma of the prostate which is intermediate or high risk, defined as possessing one or more of the following features:
Gleason >= 7
> 50% biopsy cores +
Prostate-specific antigen (PSA) >= 10
Interested in undergoing a radical prostatectomy as definitive management for prostate cancer
No clinical or radiographic evidence for distant metastatic disease
In subjects with PSA < 20 no radiographic staging is required in the absence of clinical symptoms for distant metastatic disease; for those with PSA > 20, a bone scan must document lack of concern for bone involvement

You may not qualify if…

Ineligible for surgery due to cardiac, pulmonary, or other major comorbidity factor
History of claustrophobia
Pacemaker or other implanted metal objects which would make subject ineligible for MRI, per standard criteria
Unable to give written informed consent

Where it is running

USC Norris Comprehensive Cancer Center — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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