Prophylactic Use of Postpartum Sertraline to Prevent Postpartum Depression

Stopped early · Not applicable · Has a placebo group

Conditions studied: Depression, Postpartum

In brief

The purpose of this project is to assess the effectiveness of preventative antidepressants immediately following delivery on postpartum depression rates in women at high risk due to prior history of depression or postpartum depression.

Key facts

Study ID

NCT02235064

Run by

The Cooper Health System

People needed

2

Starts

2014-07-01

Expected to finish

2015-07-01

Last updated by the study team

2018-03-29

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• Past history of depression or postpartum depression
• Singleton gestation
• Delivery > 34 weeks gestation
• No current clinical evidence of depression
• Able to read and understand written English language

You may not qualify if…

• Multiple gestation
• Delivery prior to 34 weeks
• Delivery outside of Cooper University Hospital
• Major fetal anomaly or fetal demise
• Current use of antidepressants
• Evidence of active depression at antepartum evaluation
• Edinburgh Postpartum Depression scale of >12 prior to discharge from the hospital
• Maternal age < 18 years
• Infant in Neonatal Intensive Care Unit (NICU) at time of patient discharge from hospital
• Known or suspected allergy to Sertraline

Where it is running

• Cooper University Hospital — Camden, New Jersey, United States

Full record on ClinicalTrials.gov

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