Use of Gadolinium in CT Pulmonary Angiography

Withdrawn before enrolling · Phase 4

Conditions studied: Pulmonary Embolism

In brief

The study will investigate patients with clinical suspicion for pulmonary embolism (PE) who have a contraindication to iodine based contrast. These patients normally get investigated with studies such as ultrasound and nuclear medicine studies but the fastest and preferred investigation is CT with contrast to look for filling defects in the pulmonary arteries. The investigators will assess whether gadolinium, which is currently used with MRI can be used with CT as an alternative effective contrast in diagnosis or exclusion of PE. A new type of CT scanner, a Dual Energy Scanner will be used to improve the visibility of Gadolinium contrast on CT.

Key facts

Study ID

NCT02234375

Run by

Massachusetts General Hospital

People needed

0

Starts

2017-07-01

Expected to finish

2019-12-01

Last updated by the study team

2020-02-17

Who can join

Age: 20 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients suspected of having a Pulmonary embolus
• Allergy to Iodine based intravenous contrast

You may not qualify if…

• Renal impairment
• Less than 20 years of age
• Non-English speaking
• Pregnancy
• Allergy to Gadolinium

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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