Value of Patch Testing in Direct Diet Therapy for Eosinophilic Esophagitis

Completed · Not applicable

Conditions studied: Eosinophilic Esophagitis

In brief

This study is being done to see if allergy patch testing (APT) can help predict effective dietary therapy in patients with eosinophilic esophagitis.

Key facts

Study ID

NCT02227836

Run by

Mayo Clinic

People needed

8

Starts

2014-08-01

Expected to finish

2017-09-01

Last updated by the study team

2019-04-17

Who can join

Age: 18 and older, up to 90. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults ages 18-90
• Patients with EoE, defined as dysphagia with histologic finding of greater than or equal to 15 eosinophils per high powered field (eos per HPF) on index esophageal biopsy
• Persistent symptoms and/or greater than or equal to 10 eos per HPF on esophageal biopsy after at least 8 weeks of twice daily PPI therapy

You may not qualify if…

• Patients with conditions known to be associated with esophageal eosinophilia, including Crohn's disease, Churg-Strauss, achalasia, and hypereosinophilic syndrome
• Topical swallowed steroids within 8 weeks of study enrollment
• Dermatologic conditions precluding application of Finn chambers to the skin for APT
• Inability to read due to: Blindness, cognitive dysfunction, or English language illiteracy

Where it is running

• Mayo Clinic — Rochester, Minnesota, United States

Full record on ClinicalTrials.gov

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