Vitamin D and Muscle Metabolic Function
Completed · Not applicable · Has a placebo group
Conditions studied: Healthy
In brief
The purpose of this study is to identify the magnitude of muscle lipid redistribution and muscle oxygen use in individuals 60 years old or older following combined treatment of vitamin D repletion and aerobic training compared to vitamin D repletion alone, aerobic training alone, or no treatment.
Key facts
- Study ID
- NCT02221596
- Run by
- David Travis Thomas
- People needed
- 50
- Starts
- 2014-09-01
- Expected to finish
- 2018-03-01
- Last updated by the study team
- 2018-03-15
Who can join
Age: 60 and older. Sex: any. Healthy volunteers: accepted.
You may qualify if…
- Age: 60 and older
- BMI: 18.5-29
- Communicates fluently in English
You may not qualify if…
- Metal implant not suitable for MRI
- Any form of hormone replacement therapy
- Engage in more than 1 hr/week of vigorous activity
- Participated in a high-intensity resistance or aerobic training program in the last 3 months
- Lower extremity injury or surgery in the past 3 months
- Foot sores or bone conditions severely limiting ability to move or perform exercise or joint pain made worse by mild exercise
- Diabetes, inflammatory bowel disease, renal disease or uncontrolled hypertension.
- Currently have or had a history of cardiovascular or pulmonary disease that would preclude the involvement in the performance of exercise
- History of myopathy (including congenital myopathies)
- History of neurological conditions related to spinal derangement, disk disease, peripheral neuropathies, tremor and rigidity
- Past medical history of hyperparathyroidism, kidney stones or rhabdomyolysis
- Currently receiving treatment for vitamin D deficiency
- Vitamin D level >30ng/mL
- Currently smoking
Where it is running
- University of Kentucky — Lexington, Kentucky, United States
Full record on ClinicalTrials.gov
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