Stanford RAD-AT Study (Research on Anxiety and Depression - Anhedonia Treatment)
Completed
Conditions studied: Anxiety, Depression
In brief
This research study is aimed at understanding behaviors and brain circuits that relate to anxiety and depression. Our goal is to learn which circuits of the brain are involved in anxiety and how these circuits might affect daily functioning. This study has recently added an additional treatment component: participants undergo a 12 week course of either Pramipexole medication or rTMS therapy (explained below). The ultimate goal of the study is to offer participants experiencing anxiety and depression a treatment that is alternative to ones that have failed them in the past, and to apply the knowledge we gain from investigating the brain circuits involved in anxiety and depression to help personalize treatments. We invite anyone who has recently experienced any symptoms of anxiety and/or depression to participate (no diagnosis is required to participate).
Key facts
- Study ID
- NCT02220309
- Run by
- Stanford University
- People needed
- 167
- Starts
- 2013-08-11
- Expected to finish
- 2025-04-02
- Last updated by the study team
- 2026-01-05
Who can join
Age: 18 and older, up to 65. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Recent experiences of anxiety and/or depression
- Ages 18-65
You may not qualify if…
- Specific psychiatric medications (case-by-case basis)
- A diagnosis of Bipolar 1 Disorder, Schizophrenia, or Obsessive Compulsive Disorder
- Any of the following medical conditions: Parkinson's disease; liver or kidney disease; history of epilepsy or seizures; history of cardiovascular disorders (specifically orthostatic hypotension)
Where it is running
- Gronowski Center-5150 El Camino Real — Los Altos, California, United States
- VAPAHCS/Palo Alto MIRECC-3801 Miranda Avenue — Palo Alto, California, United States
- Stanford University Department of Psychiatry — Stanford, California, United States
Full record on ClinicalTrials.gov
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