Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy

Completed · Phase 4 · Has a placebo group

Conditions studied: Delirium, Cognitive Impairment, Post-traumatic Stress Disorder, Depression, Anxiety

In brief

The purpose of this study is to investigate the effectiveness of a preventative low-dose of Haloperidol to prevent delirium in patients undergoing a esophagectomy, pneumonectomy or thoracotomy. Delirium is state of severe confusion and some symptoms include: * Cannot think clearly * Have trouble paying attention * Have a hard time understanding what is going on around them * May see or hear things that are not there. These things seem very real to them.

Key facts

Study ID

NCT02213900

Run by

Indiana University

People needed

135

Starts

2013-09-01

Expected to finish

2015-12-01

Last updated by the study team

2017-04-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• At least ≥ 18 years of age and older
• Undergoing a possible or scheduled thoracotomy
• English speaking

You may not qualify if…

• History of Schizophrenia and Parkinson's disease
• History of Severe Dementia
• History of Alcohol Abuse
• On Cholinesterase Inhibitors or Levodopa
• Pregnant or Nursing
• Corrected QT interval > 550 milliseconds at the time of randomization
• History of Neuroleptic Malignant Syndrome or Haloperidol Allergy

Where it is running

• University Hospital — Indianapolis, Indiana, United States

Full record on ClinicalTrials.gov

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