Zinc Bioavailability From Amaranth-enriched Maize Tortillas

Completed · Not applicable

Conditions studied: Nutritional Deficiency

In brief

Young children in Guatemala are at risk for nutrient deficiencies due to plant-based diets and poor sanitation. Stunting, frequent diarrhea, and respiratory infections are common. Supplementation of Zn to children during diarrhea episodes has been shown to diminish duration and severity of illness. Poor Zn absorption due to high fiber and phytate in this diet might play a role in these processes. Supplementation of this micronutrient in the diet might be beneficial. The investigators will compare absorption of Zn from white maize tortillas enriched with 20% amaranth to traditional white corn tortillas in preschool children in Guatemala.

Key facts

Study ID

NCT02208609

Run by

University of Colorado, Denver

People needed

20

Starts

2012-01-01

Expected to finish

2015-12-01

Last updated by the study team

2016-04-29

Who can join

Age: 2 and older, up to 3. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 2-3 years of age
• apparently healthy
• eats >2-3 tortillas at each meal of the day.

You may not qualify if…

• Chispitas or macrovital supplementation
• breastfeeding
• birth weight < 2,500 g
• birth defect affecting growth and development
• chronic infection
• twin or triplet
• sibling enrolled in study

Where it is running

• University of Colorado Anschutz Medical Campus — Aurora, Colorado, United States
• Universidad Francisco Marroquin — Guatemala City, Guatemala

Full record on ClinicalTrials.gov

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