Role of Cardiac Biomarkers in Prediction of Outcome in Atrial Fibrillation Patients Undergoing Catheter Ablation

Completed

Conditions studied: Atrial Fibrillation

In brief

The purpose of this study is to assess if pre-ablation levels of inflammatory biomarkers serve as independent predictors of procedure outcome To evaluate the inflammatory activation following catheter ablation by measuring serum-biomarker levels 24-hours after the procedure and examine the predictive role in procedure success To study the association of certain biomarkers with specific types of AF (paroxysmal or persistent or long standing persistent)

Key facts

Study ID

NCT02208102

Run by

Texas Cardiac Arrhythmia Research Foundation

People needed

155

Starts

2014-07-01

Expected to finish

2016-05-01

Last updated by the study team

2017-10-19

Who can join

Age: 50 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age: 50-70 years
• Patients undergoing catheter ablation of atrial fibrillation
• Able and willing to give written consent

You may not qualify if…

• Reversible causes of AF such as pericarditis and hyperthyroidism
• Associated chronic inflammatory diseases such as chronic gingivitis or peri-odontitis, rheumatoid Arthritis, IBD including Ulcerative Colitis and Crohn's disease, Lupus, Ankylosing Spondylitis, COPD, psoriasis, vasculitis
• Any other co-morbid conditions except Diabetes and hypertension
• Patients taking long-term anti-inflammatory, steroid medication, or immune suppression medication.

Where it is running

• Texas Cardiac Arrhythmia Institute, St. david's Medical Center — Austin, Texas, United States

Full record on ClinicalTrials.gov

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