Trial of Naltrexone and Dextromethorphan for Gulf War Illness
Completed · Phase 2 · Has a placebo group
Conditions studied: Gulf War Illness
In brief
Veterans of the 1991 Gulf War who developed Gulf War Illness are being studied. Treatments with FDA approved generic drugs are being administered to see if they help with the symptoms of Gulf War Illness, such as chronic fatigue; difficulty with memory, concentration, and thinking; widespread chronic pain; and autonimic dysfunction. Drugs to be tested are dextromethorphan and naltrexone.
Key facts
- Study ID
- NCT02206490
- Run by
- East Carolina University
- People needed
- 60
- Starts
- 2012-01-01
- Expected to finish
- 2016-01-01
- Last updated by the study team
- 2016-03-03
Who can join
Age: 18 and older, up to 100. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Served in the Gulf War and developed the symptoms of Gulf War Illness as described by the modified Kansas Case Definition
You may not qualify if…
- Pregnant women, nursing mothers, individuals requiring medications that have drug interactions with dextromethorphan or naltrexone, cancer not in remission, chronic infectious disease, liver disease, lupus, multiple sclerosis, stroke, under current treatment for schizophrenia, bipolar disorder/manic depression, and depression.
- Those with a history of current illicit drug use will be excluded. Individuals who have had recent surgery will not be enrolled until they have completely recovered from the surgery.
- Subjects participating in other clinical trials will be excluded.
- Those enrolled recently in a clinical trial will be enrolled after a washout period of one month.
Where it is running
- Brody School of Medicine a East Carolina Univesity — Greenville, North Carolina, United States
Full record on ClinicalTrials.gov
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