Brain-Behavior Interactions in Tic Suppression

Completed · Has a placebo group

Conditions studied: Tourette's Syndrome, Chronic Motor Tic Disorder, Chronic Vocal Tic Disorder

In brief

The purpose of this study is to examine how the brain and environment interact to influence children's ability to suppress tics using a medical technology called Transcranial Magnetic Stimulation (TMS).

Key facts

Study ID

NCT02205918

Run by

University of Minnesota

People needed

30

Starts

2017-07-01

Expected to finish

2019-09-01

Last updated by the study team

2020-07-17

Who can join

Age: 12 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Presence of motor and/or vocal tics for at least one year
• English fluency

You may not qualify if…

• Participants with medical conditions that are contraindicated for TMS (history of any known intracranial pathology, epilepsy or seizures, traumatic brain injury, brain tumor, stroke, implanted medical devices, current pregnancy or girls of childbearing age not using effective contraception, or any other serious medical conditions
• Left-handedness
• Previous diagnosis of psychosis, autism spectrum disorder, mental retardation, or cognitive disability
• Inability to undergo MRI
• Substance abuse or dependence within the past year
• History of ≥3 sessions of Habit Reversal Therapy or other treatment primarily comprised of tic suppression strategies
• Current suicidal intent
• Current neuroleptic medications, as these medications are known to lower seizure threshold

Where it is running

• University of Minnesota — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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