Prolonged Popliteal Fossa Nerve Blockade (Prolonged Pop)

Completed · Phase 1

Conditions studied: Postoperative Pain

In brief

This study looks at addition of medications to the local anesthetic for the nerve blockade.

Key facts

Study ID: NCT02198235
Run by: Hospital for Special Surgery, New York
People needed: 90
Starts: 2012-10-01
Expected to finish: 2014-02-01
Last updated by the study team: 2017-06-15

Who can join

Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Patients of Dr. Levine or Dr. Roberts at Hospital for Special Surgery
Patients aged 18-75
Patients scheduled for discharge from HSS after foot or ankle surgery
A single-injection popliteal fossa nerve block is judged appropriate
Surgery confined to foot and ankle (no iliac crest bone graft planned - iliac aspirate is not an exclusion criterion)

You may not qualify if…

< 18 and > 75
Surgery that will cause pain at sites outside the distal lower extremity (e.g. iliac crest bone graft)
Bilateral surgery
Chronic pain (defined as regular use of opioid analgesics for > 3 months)
Chronic use of steroids (defined as regular use of steroids for > 3 months)
Contraindication to performance of the popliteal fossa nerve block with 30 cc 0.25% bupivacaine (e.g. alleged bupivacaine sensitivity, low body weight, etc.)
Contraindications to dexamethasone or buprenorphine (e.g. allergy, insulin dependent diabetes mellitus, etc.)
Patients who have been diagnosed with altered pain perception or have lack of sensation
Inability of the patient to describe postoperative pain (e.g. psychiatric disorder, dementia)
Non-English speaking patients (the questionnaire is in English, and translations would have to be separately validated)

Where it is running

Hospital For Special Surgery — New York, New York, United States

Full record on ClinicalTrials.gov

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