The Effect of Experimental Dentifrices on Remineralization of Caries Lesions In-situ

Completed · Not applicable

Conditions studied: Oral Hygiene

In brief

This study will evaluate the effect of experimental sodium fluoride-silica dentifrice formulations, with and without zinc, on remineralization of enamel in situ. Following the remineralization phase, the acid resistance of the new mineral formed will be assessed. Fluoride uptake during the remineralization phase will also be measured.

Key facts

Study ID

NCT02195583

Run by

GlaxoSmithKline

People needed

62

Starts

2014-06-01

Expected to finish

2014-08-01

Last updated by the study team

2015-05-01

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Good general health with no clinically significant and relevant abnormalities of medical history or oral examination
• Participants with maxillary dental arch suitable for the retention of the palatal appliance

You may not qualify if…

• Participants taking fluoride supplement
• Pregnant or breast-feeding women

Where it is running

• GSK Investigational Site — Indianapolis, Indiana, United States

Full record on ClinicalTrials.gov

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