Canadian SCAD Study

Status unconfirmed

Conditions studied: Spontaneous Coronary Artery Dissection

In brief

SCAD (Spontaneous coronary artery dissection - tear in the arterial wall that is not related to trauma) is an under-diagnosed and poorly understood condition that mostly affects young women without common cardiovascular risk factors, and can result in heart attack and death. This observational study is designed to capture the disease's natural history and predisposing arteriopathies (medical conditions resulting in changes in the arteries), treatment strategies, long-term cardiovascular outcomes. It will also improve the diagnosis of SCAD on coronary angiography by participating clinicians, and provide guidance on investigating predisposing conditions.

Key facts

Study ID

NCT02188069

Run by

Cardiology Research UBC

People needed

750

Starts

2014-06-01

Expected to finish

2020-12-01

Last updated by the study team

2018-08-10

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients admitted with troponin-positive ACS (NSTEMI or STEMI)
• Documented NA-SCAD on coronary angiogram (including diagnosis with OCT or IVUS)

You may not qualify if…

• Patients with troponin-negative ACS
• Patients with typical atherosclerotic coronary artery disease in other coronary arterial segments with diameter stenosis ≥50%

Where it is running

• Cleveland Clinic Foundation — Cleveland, Ohio, United States
• Royal Alexandra Hospital — Edmonton, Alberta, Canada
• University of Alberta — Edmonton, Alberta, Canada
• St. Paul's Hospital — Vancouver, British Columbia, Canada
• Vancouver General Hospital — Vancouver, British Columbia, Canada
• Saint Boniface General Hospital — Winnipeg, Manitoba, Canada
• Queen Elizabeth Health Sciences Centre — Halifax, Nova Scotia, Canada
• Hamilton Health Sciences General Site — Hamilton, Ontario, Canada
• Saint Mary's — Kitchener, Ontario, Canada
• London Health Sciences — London, Ontario, Canada
• Southlake Regional Hospital — Newmarket, Ontario, Canada
• Ottawa Heart Institute — Ottawa, Ontario, Canada
• Rough Valley Health System — Scarborough Village, Ontario, Canada
• Saint Michael's Hospital — Toronto, Ontario, Canada
• Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada
• McGill University Health Centre (CUSM) — Montreal, Quebec, Canada
• Montreal Heart Institute — Montreal, Quebec, Canada
• University of Montreal (CHUM) — Montreal, Quebec, Canada
• Regina General Hospital — Regina, Saskatchewan, Canada
• Royal University Hospital — Saskatoon, Saskatchewan, Canada

Full record on ClinicalTrials.gov

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