Probiotic Use in Patients With Prior COPD Exacerbation
Withdrawn before enrolling · Not applicable · Has a placebo group
Conditions studied: COPD, Obstructive Lung Disease
In brief
The purpose of the study is to examine the hypothesis test that probiotics will reduce the frequency of exacerbation in patients with COPD.
Key facts
- Study ID
- NCT02185092
- Run by
- University of Oklahoma
- People needed
- 0
- Starts
- 2014-10-01
- Expected to finish
- 2016-12-01
- Last updated by the study team
- 2017-05-23
Who can join
Age: 18 and older, up to 99. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients admitted to OUMC or VAMC with a COPD exacerbation and pneumonia with underlying COPD will be eligible and screened.
- Patients seen in VA Chest Medicine clinic, OU Physicians clinic and Pulmonary fellows clinic at PPOB who have had a COPD exacerbation within the last year.
- Patients over age 18
- Patients who have a pulmonary function test (PFT) showing COPD within 1 year of enrollment in the study or if the treating physician plans to obtain PFT as part of the patient's care plan.
- Patients will be considered to have a diagnosis of COPD if they have a FEV1 of less than 80% of predicted and a FVC/FEV1 ratio of less than 0.70 (as defined by GOLD criteria).
You may not qualify if…
- Patients with less than one year of life expectancy from a concomitant diagnosis
- Any GI motility disorders or previous bowel resection surgery (short gut syndrome)
- Any patients with decreased immune function or on medication that may decrease immune function (other than low dose steroid or steroid taper).
- Patients admitted within the last one year with a diagnosis of pancreatitis
- Patients unable to give consent will not be included in the study.
- Patients unable to sign consent
- Patients already on azithromycin daily for COPD exacerbations
- Patients under department of corrections custody.
Where it is running
- OUHSC — Oklahoma City, Oklahoma, United States
Full record on ClinicalTrials.gov
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