Outcome Study of Highly-cross Linked Polyethylene vs. Standard Polyethylene for Primary Posterior Stabilized (PS) Total Knee

Status unconfirmed

Conditions studied: Arthroplasty, Replacement, Knee

In brief

Polyethylene wear and osteolysis remain a concern with the use of modular, fixed bearing total knee arthroplasty. A variety of highly cross-linked polyethylenes have been introduced to decrease this problem, but there is little data on the results and complications of this polyethylene in posterior-stabilized knee prosthesis. The investigators asked the following questions: (1) Are there any differences in the clinical and radiographic results when a highly cross-lined polyethylene is compared to a standard liner? (2) What is the frequency of reoperation in these two groups and are there any specific complications related to highly cross-linked polyethylene liners.

Key facts

Study ID

NCT02178020

Run by

Chapel Hill Orthopedics Surgery & Sports Medicine

People needed

500

Starts

2009-07-01

Expected to finish

2019-07-01

Last updated by the study team

2017-02-01

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• all patients indicated for primary total posterior stabilized knee arthroplasty

You may not qualify if…

• patients who refused participation
• patients who did not comprehend the English language to give informed consent
• patients with severe knee deformity thought to require a primary constrained condylar prosthesis

Where it is running

• Chapel Hill Orthopedic Surgery and Sports Medicine — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

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