High-Dose Lymph Node Intensity Modulated Radiation Therapy and Hypofractionated Prostate (SIB)

Running, not enrolling · Not applicable

Conditions studied: Prostate Cancer

In brief

The purpose of this study is to find out the effects (good and bad) of using newer technologies that allow very precise delivery of radiation. These newer technologies are Intensity Modulated Radiation Therapy (IMRT) and Image Guided Radiation Therapy (IGRT).

Key facts

Study ID

NCT02177292

Run by

Medical College of Wisconsin

People needed

80

Starts

2010-06-23

Expected to finish

2026-08-17

Last updated by the study team

2026-05-26

Who can join

Age: 18 and older. Sex: male. Healthy volunteers: not accepted.

You may qualify if…

• Histologically confirmed, adenocarcinoma of the prostate
• T1-2N0M0 with risk of pelvic lymph nodes involvement >25% by Roach formula [(2/3xPSA) + (Gleason Score - 6)x10], or any T3-4N0M0
• Karnofsky Performance Scale > 70.
• Prostate tumor biopsy grading by Gleason score classification is mandatory prior to registration.
• No prior pelvic or prostate radiation or chemotherapy for any reason; induction hormonal therapy prior to registration is acceptable.
• Patients must sign a study-specific consent form prior to registration.
• No evidence of distant metastases (Bone scanning)

You may not qualify if…

• Clinical or pathological evidence of distant metastases (M1).
• Radical surgery for carcinoma of the prostate
• History of prior chemotherapy
• History of prior pelvic radiation therapy
• Children (age < 18).

Where it is running

• Froedtert & the Medical College of Wisconsin — Milwaukee, Wisconsin, United States

Full record on ClinicalTrials.gov

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