Low-Fat Diet and Fish Oil in Men on Active Surveillance for Prostate Cancer
Running, not enrolling · Not applicable
Conditions studied: Adenocarcinoma of the Prostate, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
In brief
This randomized phase II trial will evaluate if a low omega-6, high omega-3 fat diet combined with fish oil has the potential to delay disease progression in patients with prostate cancer undergoing active surveillance.
Key facts
- Study ID
- NCT02176902
- Run by
- Jonsson Comprehensive Cancer Center
- People needed
- 107
- Starts
- 2014-11-01
- Expected to finish
- 2026-11-01
- Last updated by the study team
- 2025-02-10
Who can join
Age: 50 and older, up to 80. Sex: male. Healthy volunteers: not accepted.
You may qualify if…
- Patients sign the informed consent
- Patient had a prostate biopsy performed by Dr. Mark with the Artemis device and has adenocarcinoma of the prostate
- Patient elects to undergo active surveillance
- Clinical stage T2c or less
- Gleason grade 3+4 or less
- PSA < 25
- Geographically able to have study visits at the University of California, Los Angeles (UCLA) Clinical Research Unit
- Subjects are willing to not consume lycopene, green tea or pomegranate supplements or pomegranate juice during the 1-year study
- If subjects are randomized to the control group they agree to not consume fish oil capsules during the 1-year study
You may not qualify if…
- Diagnostic prostate biopsy with only 1 core with cancer and < 5% of tissue from that core involved with cancer
- Patient has taken finasteride or dutasteride during the prior year
- Patient has taken fish oil during the prior 3 months
- Patient had prior treatment for prostate cancer (surgery, radiation, local ablative therapy, anti-androgen therapy or androgen deprivation therapy)
- Patient has other medical conditions that exclude him from undergoing a repeat prostate biopsy at 1-year
- Patient has allergy to fish
Where it is running
- Jonsson Comprehensive Cancer Center — Los Angeles, California, United States
Full record on ClinicalTrials.gov
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