Mediterranean Diet and Protein-Sparing Modified Diet for Metabolic Syndrome in Liver Transplant Recipients

Stopped early · Not applicable

Conditions studied: Liver Transplantation, Metabolic Syndrome X, Obesity

In brief

Many metabolic complications can develop after liver transplant including: diabetes, high blood pressure, obesity, heart attacks and stroke. The goal of this study is to look at the safety and effect of 2 well known and established diet regimens on the people who had a prior liver transplant and investigate whether it helps with the control of these comorbidities.

Key facts

Study ID: NCT02174783
Run by: The Cleveland Clinic
People needed: 25
Starts: 2014-06-01
Expected to finish: 2015-04-01
Last updated by the study team: 2017-03-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

Adult patients > 18 years old who had a successful liver transplant at least 1 year prior to enrollment who also have a BMI>30 with previous failed attempts at weight loss via conventional methods. In addition to one of the following:
Triglyceride (TG)>150 mg/dl or specific treatment for this lipid abnormality
HDL <40 mg/dl in females and <50 mg/dl in males or specific treatment of this lipid abnormality
Systolic BP >130 or diastolic BP >85 mm Hg or treatment for previously diagnosed hypertension
Fasting plasma glucose >100 mg/dl or previously diagnosed type 12 diabetes

You may not qualify if…

Significant behavioral issues that would interfere with compliance
Lack of readiness to change (pre-contemplation, contemplation or preparation stages)
Previous bariatric surgery
Pregnant or planning to become pregnant
History of a documented eating disorder (e.g. bulimia)
History of kidney stones

Where it is running

Cleveland Clinic — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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