Intubated ICU Patients

Stopped early

Conditions studied: Patients Requiring Endotracheal Intubation

In brief

The purpose of this research study is to determine how cell changes during endotracheal intubation and artificial lung ventilation affect lung inflammation. Patients will undergo placement of an endotracheal tube (ETT) as standard of care. Tracheal (windpipe) lavage will be obtained each day for up to 72 hours. Lung samples or fiberoptic (lung) samples will be collected at the same time intervals when possible and if they are done as standard of care. Blood samples will be obtained simultaneous with the collection of the trachael (windpipe) specimens.

Key facts

Study ID

NCT02171091

Run by

Washington University School of Medicine

People needed

8

Starts

2016-12-01

Expected to finish

2017-08-08

Last updated by the study team

2018-11-15

Who can join

Age: 18 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Ages 18 to 85
• Required to have endotracheal intubation
• Admitted to an intensive care unit

You may not qualify if…

• On immunosuppressive medications
• Previous tracheal surgery
• On azithromycin
• Pregnancy
• Cancer

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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