Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus

Completed · Phase 2 · Has a placebo group

Conditions studied: Dyspepsia, Diabetes Mellitus With Gastrointestinal Symptoms

In brief

The purpose of this study is to understand why people with indigestion have gastrointestinal symptoms and in particular to understand whether symptoms are related to increased sensitivity to nutrients in the small intestine and to a hormone (GLP1) which is normally released from the small intestine in response to nutrients. We propose to study the contribution of GLP1 to intestinal sensitivity with a drug (exendin 9-39) that blocks the effects of GLP1.

Key facts

Study ID
NCT02170870
Run by
Mayo Clinic
People needed
104
Starts
2014-06-01
Expected to finish
2017-11-17
Last updated by the study team
2019-04-23

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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