Molecular Autopsy Study

Recruiting now

Conditions studied: Sudden Unexplained Death

In brief

This study seeks to incorporate genetic testing into the postmortem examination of cases of sudden unexplained death.

Key facts

Study ID

NCT02168088

Run by

Scripps Translational Science Institute

People needed

100

Starts

2014-06-01

Expected to finish

2030-06-01

Last updated by the study team

2025-01-16

Who can join

Age: any, up to 45. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Index case age between birth - 45 years
• Clinical presentation of sudden / unexplained death (believed to be cardiac in nature OR secondary to a massive unprovoked pulmonary embolism with no prior diagnosis of prothrombotic disease)

You may not qualify if…

• Premature death secondary to murder, suicide or external causal event
• Premature death thought secondary to known chronic comorbid medical condition
• Premature death thought secondary to end-organ failure (kidney, liver, lung) other than heart
• Previously diagnosed with hypertrophic cardiomyopathy (HCM)
• Prior myocardial infarction (regardless of stenting or bypass)
• Prior cerebrovascular accident (stroke or TIA)
• History of open heart surgery (for any reason)
• History of severe, untreated hypertensive heart disease
• History of illicit drug use
• History of heavy alcohol abuse
• History of severe pulmonary disease
• History of morbid obesity

Where it is running

• Scripps Translational Science Institute — La Jolla, California, United States (enrolling)

Full record on ClinicalTrials.gov

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