The Impact of a Physical Activity Program on Biomarkers of Aging During Chemotherapy for Breast Cancer

Completed

Conditions studied: Breast Cancer, Aging

In brief

This study will look at whether or not participating in a physical activity intervention during chemotherapy for breast cancer can prevent a marker of aging called p16 from having a large increase after chemotherapy.

Key facts

Study ID: NCT02167932
Run by: UNC Lineberger Comprehensive Cancer Center
People needed: 127
Starts: 2014-03-01
Expected to finish: 2016-11-30
Last updated by the study team: 2018-06-06

Who can join

Age: 21 and older, up to 59. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

21 to 59 years of age, female (A similar trial LCCC 1226 explores physical activity in women 60 years and older and is now in progress.
Histologically confirmed Stage I, II or III breast cancer (if the patient has had more than one breast cancer, then the most recent diagnosis)
Scheduled to begin an appropriate adjuvant or neo-adjuvant chemotherapy regimen as defined by NCCN guidelines (www.nccn.org). Patients receiving anti-HER-2 therapy are eligible but the intervention will only be tested during the chemotherapy portion of the regimen.
English speaking
IRB approved, signed written informed consent
Approval from their treating physician to engage in moderate-intensity physical activity
Patient-assessed ability to walk and engage in moderate physical activity
Willing and able to meet all study requirements.

You may not qualify if…

One or more significant medical conditions that in the physician's judgment preclude participation in the walking or strength training intervention.
Unable to walk or engage in moderate-intensity physical activity.

Where it is running

University of North Carolina — Chapel Hill, North Carolina, United States

Full record on ClinicalTrials.gov

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