Ischemic Preconditioning to Prevent Acute Kidney Injury

Completed · Not applicable

Conditions studied: Acute Kidney Injury

In brief

The purpose of this study is to learn about the impact of ischemic preconditioning in reducing contrast induced kidney damage in people with pre-existing kidney problems who are undergoing cardiac catheterization procedures.

Key facts

Study ID

NCT02167152

Run by

University of Kansas Medical Center

People needed

115

Starts

2014-06-01

Expected to finish

2016-02-01

Last updated by the study team

2018-04-04

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Stage III-IV chronic kidney disease (with serum creatinine at or above 1.4 mg/dl and eGFR 15-55 ml/min/1.73m2 calculated by the Modification of Diet in Renal Disease formula)
• Undergoing planned coronary angiography (including both cardiac and peripheral vascular) and/or intervention at KUMC

You may not qualify if…

• Patients with normal renal function (stage 0 to 2 chronic kidney disease and/or serum creatinine less than 1.4 mg/dl)
• Inability or unwillingness to provide consent
• Patients undergoing hemodialysis or peritoneal dialysis therapy
• Patients with renal artery stenting
• Hemodynamically unstable patients
• Patients with acute or acute on chronic heart failure
• Patients who are unable to undergo the study procedure due to any upper extremity problems such as prior amputation, prior radical mastectomy, etc
• Patients who have not been hydrated prior to procedure using the standard protocols

Where it is running

• University of Kansas Medical Center — Kansas City, Kansas, United States

Full record on ClinicalTrials.gov

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