Hypoxia Inducible Factor 1 Alpha as a Novel Biomarker in Septic Shock

Completed

Conditions studied: Sepsis

In brief

The purpose of this research study is to determine if a chemical marker in the blood, hypoxia-inducible factor (HIF-1 alpha), can be used to predict subject's hospital outcomes when the subject is diagnosed with sepsis. Sepsis is defined as either the presence of pathogenic organisms or their toxins in the blood and tissues. Sepsis is one of the most significant challenges in critical care medicine. The investigators propose that hypoxia-induced expression of HIF-1 alpha will correlate with the clinical features of Sepsis and in the future, HIF-1 alpha may be used as a biomarker in Sepsis.

Key facts

Study ID
NCT02163473
Run by
University of Florida
People needed
63
Starts
2013-01-01
Expected to finish
2015-06-01
Last updated by the study team
2016-10-13

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: accepted.

Where it is running

Full record on ClinicalTrials.gov

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