Videocapillaroscopy Assessment During Systemic Agent Therapy in Psoriasis

Completed

Conditions studied: Psoriasis

In brief

The aim of this study is to determine if videocapillaroscopy could be used as an objective and reliable method to assess psoriasis severity and to document improvement during treatment by measuring changes in vascular features.

Key facts

Study ID

NCT02162472

Run by

Northwestern University

People needed

19

Starts

2015-07-01

Expected to finish

2021-12-31

Last updated by the study team

2022-01-11

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Subjects with a clinical diagnosis of chronic active plaque psoriasis
• Subjects eligible for systemic monotherapy (oral or biologic agents).
• Subjects with evidence of characteristic vascular alterations on capillaroscopic examination.
• Subjects who are able to complete the study visits and procedures, including completion of the DLQI questionnaire.
• Subjects who are willing to have standardized digital photographs taken of 2 different target plaque lesions on the extremities.
• Subjects who are willing to have videocapillaroscopic photographs taken of 2 different target plaque lesions as well as of 2 areas of uninvolved skin on the extremities.
• Subjects who have had a "4 week" washout period if they have recently changed systemic psoriatic therapy.

You may not qualify if…

• Those who do not fit the inclusion criteria.
• Subjects who are unable to understand the protocol or give informed consent.

Where it is running

• Northwestern University, Department of Dermatology — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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